I. Basic Information

　　Project Subject: Institute of Zoology, Chinese Academy of Sciences

　　Category: Major scientific facilities (proposed)

　　Location: Central Area of Huairou Science City

　　Area: 53.25 mu

　　Building area: 94,580 m2

　　Total investment: 2,640.92 million yuan

　　Subject orientation: life science

Rendering of the Human Organ Physiopathology Emulation System

Main Contents

　　Project introduction: The Human Organ Physiopathology Emulation System (HOPE) has been developed to provide an accurate simulation of the physiological and pathological states of the human body, as well as a comprehensive analysis of the complex functions and regulatory mechanisms of the human body. This system is of great significance for life science research and biomedical research and development.

This facility emulates the structures and functions of organs and tissues in the body by preparing organ components and connecting them in a physiological manner to simulate the connections between human organs. It also incorporates technologies such as large-scale in vitro maintenance of functions and big data fitting to simulate physiological and pathological states of multiple genetic backgrounds. This provides a standardised and open application environment for disease mechanisms, drug evaluation, and regenerative medicine.

　　Four core systems are to be built, namely the organ component manufacturing system, the organ function simulation system, the user-customised application system, and the centralised service station.