Huairou Science City Sci-Tech Innovation Update (Issue No. 12)

Date:2025-10-24 Source:Huairou Science City
Peking University’s School of Physics proposes a new phase-matching theory for solid-state high-harmonic generation
Recently, a research team led by CAS Member Wang Enge from the International Center for Quantum Materials at Peking University’s School of Physics, along with Researcher Liu Kaihui from the Institute of Condensed Matter Physics and Materials Physics and Associate Researcher Hong Hao, made significant progress in the field of solid-state high-harmonic generation (HHG). For the first time, the team introduced a nonlinear geometric phase by twisting the layers of van der Waals crystals, achieving phase matching in solid-state HHG. This breakthrough provides a crucial boost to the development of all-solid-state attosecond and extreme ultraviolet (EUV) laser sources. The related research findings have been published in Physical Review Letters.
Source: Peking University’s School of Physics
Earth System Numerical Simulation Facility (EarthLab) supports development of high-performance dynamical core LMARSpy
With support from the national major sci-tech infrastructure “Earth System Numerical Simulation Facility” (EarthLab), a research team led by Researcher Chen Xi at the State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics, Institute of Atmospheric Physics, Chinese Academy of Sciences, independently developed the high-performance dynamical core LMARPy. The framework employs a low-Mach-number Riemann solver tailored for atmospheric applications to solve the compressible Euler equations, delivering both high accuracy and strong stability. It offers a GPU-ready algorithmic solution to key challenges in global kilometer-scale non-hydrostatic modeling and lays a solid foundation for next-generation general-circulation and regional models. Thanks to its machine-learning-based extensibility, LMARPy can also be deeply integrated with large AI models, propelling numerical weather prediction into an intelligent new era. The findings appear in the Journal of Advances in Modeling Earth Systems (JAMES).
Source: Earth System Numerical Simulation Facility
Beijing Institute for Stem Cell and Regenerative Medicine reveals vitamin C’s protective effect against primate ovarian aging
Researchers from the Beijing Institute for Stem Cell and Regenerative Medicine / Institute of Zoology, Chinese Academy of Sciences—Researcher Liu Guanghui, Researcher Qu Jing and collaborators—have discovered that vitamin C protects primate ovaries from aging. In a 3.3-year intervention study, the team demonstrated for the first time in a primate model that clinically safe oral doses of vitamin C significantly delay ovarian aging. They further elucidated the molecular mechanism: vitamin C activates the NRF2 signaling pathway to exert its protective effects. The study provides both theoretical and experimental groundwork for future nutritional interventions, drug development and cell-therapy strategies targeting female reproductive aging. The results are published in Cell Stem Cell.
Source: Beijing Institute for Stem Cell and Regenerative Medicine
Beijing Institute for Stem Cell and Regenerative Medicine proposes an AI-driven strategy to resurrect traits of extinct species
With advances in gene editing and stem-cell technologies, reviving certain traits of extinct organisms has become a cutting-edge bioengineering goal. Researcher Li Wei and Researcher Feng Guihai from the Beijing Institute for Stem Cell and Regenerative Medicine / Institute of Zoology, Chinese Academy of Sciences, systematically reviewed current approaches to functional de-extinction and their technical hurdles. They propose a forward-looking framework that integrates generative artificial intelligence, synthetic biology and stem-cell technology, offering a novel route that complements existing strategies and collectively advances the functional resurrection of extinct traits. The perspective appears in Trends in Biotechnology.
Source: Beijing Institute for Stem Cell and Regenerative Medicine
Institute of Mechanics achieves new progress in additively manufactured hierarchical heterogeneous 316L stainless steel
Assistant Researcher Li Na, Researcher Li Yujiong and Researcher Wei Yujie at the Institute of Mechanics, Chinese Academy of Sciences, introduced an ultrasonic-coupled additive-manufacturing technique. Leveraging the cavitation effect generated by ultrasonic waves to increase under-cooling at the solid–liquid interface, the team built an external ultrasonic field and coupled it to an additive-manufacturing system. This approach enables active control of characteristic microstructural dimensions, promotes the transition from columnar to equiaxed grains and refines grain size. The work realizes tunable, multi-level heterogeneous microstructures and opens a new path for microstructure design and manufacturing. The findings are reported in the International Journal of Plasticity.
Source: Institute of Mechanics, Chinese Academy of Sciences